Immune monitoring technology primer: clinical validation for predictive markers
نویسندگان
چکیده
منابع مشابه
Immune monitoring technology primer: clinical validation for predictive markers
Background: Recent biotechnological developments have resulted in increasing interest in immunology biomarkers. These biomarkers have potential clinical utility in the near future as predictors of treatment response. Hence, clinical validation of these predictive markers is critical. Findings: The process of clinically validating a predictive biomarker is reviewed. Validation of a predictive bi...
متن کاملImmune monitoring technology primer
BACKGROUND Recent biotechnological developments have resulted in increasing interest in immunology biomarkers. These biomarkers have potential clinical utility in the near future as predictors of treatment response. Hence, clinical validation of these predictive markers is critical. FINDINGS The process of clinically validating a predictive biomarker is reviewed. Validation of a predictive bi...
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BACKGROUND Profiling of the immune receptor repertoire is becoming increasingly relevant to the understanding and clinical management of cancer, autoimmunity, aging, and infectious disease. FINDINGS A platform technology is described that provides comprehensive immune receptor profiling. CONCLUSION Immunosequencing is a platform technology that allows the enumeration, specification and quan...
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Description of the technology Protein microarrays are used to identify targets of drugs, small molecules, and enzyme substrates that may be modified in numerous ways such as by phosphorylation or methylation, to detect protein binding properties, investigate protein-protein interactions, and to define protein-based biomarkers in a high-throughput manner. They are based on the development of DNA...
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ژورنال
عنوان ژورنال: Journal for ImmunoTherapy of Cancer
سال: 2015
ISSN: 2051-1426
DOI: 10.1186/s40425-015-0086-9